dementia
In past articles (please see links below), I have examined lifestyle, exercise, nutritional, and supplement interventions to support neurological conditions such as dementia and Alzheimer’s disease. Emerging evidence is suggesting the potential efficacy of an eating protocol known as time-restricted feeding (TRF) to help manage such conditions. As a means of appreciating TRF and its…
Alzheimer’s disease (AD) is a condition characterized by the development of two abnormal proteins in the brain known as β-amyloid and tau, which are toxic to nerve cells within the brain.1 The build-up of such proteins inexorably leads to neuron death, degraded brain function, and manifestations of dementia; a general term, which describes a decline in mental abilities…
INTRODUCTION Mitochondria are organelles (subcellular structures conducting specific tasks) found within the cells of our bodies. Such organelles are involved in several critical processes to include reactive oxygen species (ROS) production, cell survival, cell signalling, apoptosis (cell death), several metabolic pathways, and energy production via adenosine triphosphate (ATP) synthesis; its most widely known contribution.1,2 As…
AD is characterized by an increase in beta-amyloid plaque deposition and hyperphosphorylated tau proteins along neurons of the brain, in addition to increased inflammation from oxidative stress.1(2) Left unmitigated, neurodegeneration from the above mechanisms slowly degrades communication, writing, and reading while also destabilizing both physical and emotional control in the most severe stages of AD.1(7)2…
Dementia is one of the predominant health problems within populations of advanced age, afflicting 5-10% of individuals with said disease.1 As many as 35.6 million individuals have dementia globally, and it has been estimated that said number will increase to 65.7 million by 2030.1(508) Hence, it is imperative that individuals with such a condition explore…
Knee osteoarthritis (KO) is one of the most common conditions affecting approximately 30-50% of individuals over 65 years of age.1 KO is a chronic and degenerative process which is characterized by articular cartilage degeneration, injury, narrowing of articular space, and inflammation.1(1-2) In recent years, researchers have placed particular focus upon the inflammatory cascades associated with…
Consistent sleep quality and duration are cornerstones of both health and quality of life. Humans require appropriate sleep, each night, in order to synthesize hormones, repair tissues, grow tissues, and maintain cognitive function, memory, and mood.1 Thus, disruptions in sleep quality and duration can induce aberrations in health and homeostasis, demanding interventions to help restore…
Sleep is a critical, yet often underappreciated, constituent of health and homeostasis. In many industrialized societies, however, a trend towards less hours of sleep per night has become more prevalent.1 Seven hours or less of sleep has been attributed to factors such as greater time associated with leisure activities and longer work schedules.1(148) Ultimately, such…
The World Alzheimer Report (2016) stated that approximately 47 million people suffer with dementia, worldwide.1 Furthermore, said statistic was predicted to increase in excess of 131 million by the year 2050, while the population of individuals aged 65 and older continue to rise across the world.1(1) In this author’s previous posts, nutritional and sleep hygiene interventions…
Parkinson’s disease (PD) is the second most common neurodegenerative disorder where neurons that make the neurotransmitter dopamine, responsible for human movement, are destroyed.1,2 Furthermore, such a condition has reached and affected approximately 4 million individuals, worldwide.1(120) Said condition is progressive in nature and characterized by a multisystem disorder affecting vulnerable populations, suspected to double in…