Neurological / Psychological
Small intestinal bacterial overgrowth (SIBO) is characterized by an overpopulation (in excess of 105– 106) of bacteria in the small intestine and stomach (Khalighi et al., 2014; Nabanan & Fauzi, 2015). Several urinary organic acid biomarkers are available which help determine the presence and overpopulation of such bacterial species. Such knowledge is critical as it…
In my last post, I outlined possible causes of metabolic syndrome (MS) as well as pathophysiological manifestations of said condition, to include dysregulation of fatty acid synthesis (dyslipidemia). One cause of dyslipidemia includes an overabundance of insulin production, which is also a marker of MS (Lord & Bralley, 2012). However, it is also possible that…
The gastrointestinal tract (GIT) is an estimated 16-foot long system, which includes the upper digestive tract (esophagus, oral cavity, stomach) in addition to the lower digestive tract (small and large intestine) and accessory organs (liver, gallbladder, pancreas) (Gropper, Smith, & Carr, 2018). Such a system serves as a semipermeable gateway connecting the outside environment to…
Iodide (I) is a non-metal responsible for many roles to include thyroid hormone synthesis; a substance influencing several physiological processes to include stimulation of oxygen consumption, body heat production, nervous system development, and maintenance of basal metabolism (Gropper, Smith, & Carr, 2018; Weng, Liu, Ye, Pan, & Xia, 2014). Thus, adequate consumption I is essential…
Mitochondria are organelles found within cells responsible for energy (ATP) production. Such is achieved via conversion of food (carbohydrates, fats, proteins) through oxidation and enzymatic reactions (Reisner & Reisner, 2017). As such, it is paramount said enzymes are present and in adequate concentrations, which is achieved by appropriate levels of key precursors; zinc (Zn) and…
Zinc (Zn) is a micronutrient and essential cofactor/metal in many enzymes to include alkaline phosphatase, carbonic dehydratase, and polymerases and is obligatory for cell division and DNA synthesis (Crook, 2011). Deficiencies in Zn can cause several maladies such as increased risk of infections, infertility, impaired brain development, dermatitis, alopecia, low testosterone, and impaired smell/taste (Crook,…
Potassium (K) is a micronutrient, which is a constituent of a larger family of electrolytes to include phosphorus (P), chloride (Cl), calcium (Ca), and sodium (Na) (Gropper, Smith, & Carr, 2018). When in balanced concentrations, electrolytes facilitate nerve conduction, movement of nutrients within a cell, pH balance, and fluid balance (Fluid and Electrolyte Balance, 2018)….
Magnesium (Mg) is a mineral found among a group of electrolytes to include potassium (K), sodium (Na), calcium (Ca), chloride (Cl), and phosphorus (P) (Maday, 2013). As an aggregate, electrolytes play a central role in balancing fluids, pH, transportation of nutrients and metabolites within the cell, and nerve conduction (Fluid and Electrolyte Balance, 2018). Considering…
Pyridoxine (B6), is a micronutrient which serves as a coenzyme in over 100 enzymes (Grooper, Smith, & Carr, 2018). Furthermore, its primary role is found in the metabolism of glucose, carnitine, neurotransmitters, heme, nucleic acids, sphingolipids, and amino acids (Gropper et al., 2018). Considering B6’s integral role as a coenzyme and its involvement in energy/neurotransmitter…
B9, also known as folate, is a water-soluble micronutrient central to health and homeostasis (Sanvisens et al., 2017). Functions include the metabolism of nutrients such as choline, amino acids, pyrimidines, purines, DNA synthesis/repair, and cell division (Gropper, Smith, & Carr, 2018). As such, deficiencies in folate can lead to disruptions in said functions. As a…